Strength product:Fenbendazole Appearance:It is white or white alike powder
Quality standard: CPV2010
Properties:
This product belongs to benzimidazole class. It has broad-spectrum antiscolic effect. Nematode is sensitive to it, and it also has strong effect on cestode and trematode, but no effect on schistosome. Its effect mechanism mainly is that this product will function when combined with canaliculus albumen of eelworm. After be taken orally, only little of it was absorbed. Ruminant is slow while single-stomach animal is quick. Taken orally, the blood concentration will reach the peak: dog 24 hours; sheep 2-3 days. The absorbed parts will metabolize to sulfoxide (active Oxfendazole ) and sulfone. In cattle, sheep and pig, 44%-55% benzimidazole will excrete along with the dejecta in the form of original form and less than 1% excretes in the urine.
Application:
Nematodiasis, cestodediasis and trematodiasis of the animal.
Storage:Keep container tightly closed in a cool, well-ventilated area.
Pharmacological action:
Fenbendazole is only marginally absorbed after oral administration. After absorption, fenbendazole is metabolized to the active compounds, oxfendazole (sulfoxide) and the sulfone.
Fenbendazole is a benzimidazole group of antinematodal group that exerts its action by inhibiting fumerate reductase production by parasites which then results in muscle paralysis to the parasites.
Therapeutic indications:
Fenbendazole is a broad-spectrum anthelmintic effective against mature immature gastrointestinal nematodes and lungworms. Fenbendazole is effective against round worms of Horse, cattle, sheep, goats, and pigs. Fenbendazole has also ovicidal properties and is the primary choice of drug against hypobiotic of Ostertagia, as well as against strains which are resistant to other benzimidazoles. It also eliminates lung worms and tape worms and kills all mature and immature worms.
It is effective against Talinia (dog), Moniezia (cattle), coenurus of T.muticeps (sheep), and T. Saginata (cattle)
China (Mainland)
